Thursday, February 28, 2013

Fusion as an energy source? Physicists demonstrate the acceleration of electrons by a laser in a vacuum

Feb. 27, 2013 ? Accelerating a free electron with a laser has been a longtime goal of solid-state physicists. David Cline, a distinguished professor in the UCLA Department of Physics and Astronomy, and Xiaoping Ding, an assistant researcher at UCLA, have conducted research at Brookhaven National Laboratory in New York and have established that an electron beam can be accelerated by a laser in free space.

This has never been done before at high energies and represents a significant breakthrough, Cline said, adding that it also may have implications for fusion as a new energy source.

In free space, a plane-wave laser is unable to accelerate an electron, according to the Lawson-Woodward theorem, posited in 1979. However, Yu-kun Ho, a professor at China's Fudan University in Shanghai, and his research group have proposed a concept of what physicists refer to as the capture-acceleration scenario to show that an electron can be accelerated by a tightly focused laser in a vacuum.

In the capture-acceleration scenario, the diffraction from a tightly focused laser changes not only the intensity distribution of the laser but also its phase distribution, which results in the field phase velocity being lower than the speed of light in a vacuum in some areas.

Thus, a channel that overlaps features of both strong longitudinal electric field and low-laser-phase velocity is created, and electrons can receive energy gain from the laser. The acceleration effect increases along with increasing laser intensity, Cline said. This channel for electrons may be useful for other scientific endeavors, such as guiding an electron beam into a specific region of laser fusion applications, he said.

A possible application of this discovery is the use of laser plasma fusion to provide a new energy source for the U.S. and other countries. The focus of the laser generates a natural channel that can capture electrons and drive them into a pellet that explodes, by fusion, to produce excess energy, Cline said.

With federal funding from the U.S. Department of Energy, a project to carry out a proof-of-principle beam test for the novel vacuum acceleration at Brookhaven National Laboratory's Accelerator Test Facility (BNL-ATF) has been proposed and approved -- a collaboration among the UCLA Center for Advanced Accelerators, of which Cline is principal investigator, Ho's group and the Accelerator Test Facility team.

BNL-ATF is one of the few facilities that can provide both a high-quality electron beam and a high-intensity laser beam for the beam test, Cline said. Ho's group provides theoretical support. UCLA scientists -- Cline, Ding and Lei Shao, a former UCLA physics graduate student of Cline's -- are responsible for the whole experiment and the experimental data analysis.

Simulation research work and hardware design have been done in accordance with BNL-ATF's experimental conditions. The simulation results predict that vacuum laser acceleration phenomena can be observed with ATF's diagnostic system.

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The above story is reprinted from materials provided by University of California - Los Angeles.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal References:

  1. L. Shao, D. Cline, X. Ding, Y.K. Ho, Q. Kong, J.J. Xu, I. Pogorelsky, V. Yakimenko, K. Kusche. Simulation prediction and experiment setup of vacuum laser acceleration at Brookhaven National Lab-Accelerator Test Facility. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2013; 701: 25 DOI: 10.1016/j.nima.2012.09.053
  2. David Cline, Lei Shao, Xiaoping Ding, Yukun Ho, Qing Kong, Pingxiao Wang. First Observation of Acceleration of Electrons by a Laser in a Vacuum. Journal of Modern Physics, 2013; 04 (01): 1 DOI: 10.4236/jmp.2013.41001

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/oRWFsnC7UMg/130228093833.htm

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Multitasking Problem On iOS - Business Insider

As popular as Apple's iOS operating system for iPhones and iPads is, it functions largely the same as it did when it was first introduced more than six years ago.

That normally wouldn't be a big deal, but as mobile OS usage eats into normal PC OS usage, it's becoming more apparent that Apple still has a lot of work to do when it comes to productivity, content creation, and multitasking.

Kontra of Counternotions, a really smart anonymous blogger who comments on Apple design a lot, has a new post on the multitasking issue in iOS.

Here's the key paragraph that demonstrates just how difficult it is to work between multiple apps:

In iOS, this involves double-clicking the Home button, swiping in the tray to find the other app, waiting for it to (re)load fully, locating the app view necessary to copy, double-clicking the Home button, finding the previous app in the tray and waiting for it to (re)load fully to paste the previously copied material. That?s just one operation between two apps. Composing a patient review for a doctor or creating a presentation for a student can easily involve many such operations among multiple apps.

What a pain.

Kontra has a temporary solution that Apple could implement in its next version of iOS, which is expected to launch as early as this summer. Apple could add what Kontra calls a "multi-slot clipboard" that would let you copy multiple items at once before plugging them into another app. It seems like such a feature would be easy for Apple to add without confusing users. Plus it'll give Apple another full year to figure out a more robust way to multitask.

But even as Apple lags behind, some of its biggest competitors are already addressing multitasking on the touchscreen in their latest smartphones and tablets.

Microsoft's new Windows 8 operating system, which was designed primarily for touchscreen devices, has a unique multitasking feature that lets you "snap" any app to the side of your display. It's also very easy to cycle between apps in Windows 8 by swiping your finger from the left to right side of your screen.

Samsung's Galaxy Note 10.1 and 8.0 Android tablets also let you run two apps at once in a split screen, although there are only about 20 apps that utilize that feature right now. Some of Samsung's Galaxy smartphones like the Galaxy S III let you run multiple apps at once in separate windows.

Finally, BlackBerry's new operating system, BlackBerry 10, has the best multitasking function we've ever seen on a smartphone. Swiping from the bottom to the top of the screen reveals the apps you have running in the background, making it incredibly easy to switch between them.

Yes, adding a more robust multitasking solution to iOS could alienate and confuse some people who have become familiar with the operating system over the years. Just look at all the confusion Microsoft caused with its radical new Windows 8 design.?

But if tablets are going to eventually replace regular laptops and PCs for most users, multitasking and productivity are two very important things Apple will have to expand on.

Source: http://www.businessinsider.com/multitasking-problem-on-ios-2013-2

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Target 4Q adj. profit beats Wall Street's view

MINNEAPOLIS (AP) ? Target's fiscal fourth-quarter net income dipped 2 percent as it dealt with intense competition during the crucial holiday season. But its adjusted results beat analysts' estimates and it forecast first-quarter earnings above Wall Street's view.

Shares rose almost 2 percent in premarket trading Wednesday.

The Minneapolis-based company earned $961 million, or $1.47 per share, for the period ended Feb. 2. That's down from $981 million, or $1.45 per share, a year earlier.

Removing certain items, earnings were $1.65 per share. That tops analysts' forecast for earnings of $1.47 per share.

Revenue climbed 7 percent to $22.73 billion from $21.29 billion. This met Wall Street's expectations.

Target Corp. foresees first quarter adjusted earnings of $1.10 to $1.20 per share.

Analysts predict earnings of $1.05 per share.

Source: http://news.yahoo.com/target-4q-adj-profit-beats-wall-streets-view-125353190--finance.html

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Monday, February 25, 2013

Watch out for flooding on water on Huger, President, Hagood, Smith, and Keats. L...

Steer clear of downtown flooding

www.charlestoncitypaper.com

As expected, there is some flooding on downtown streets after this morning's downpour. According to a Charleston police spokesman, the roads were "pretty good" after high tide at 6 a.m. this morning, but at 12:45 p.m., there were reports of flooding in certain low-lying areas.

Source: http://www.facebook.com/charlestoncitypaper/posts/429523257122932

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Sunday, February 24, 2013

In Wyoming, a bare-knuckle fight for control of education

CODY, Wyoming (Reuters) - Thinly populated Wyoming is embroiled in debate over how to manage a school system that has achieved only moderate gains in test scores despite having one of the top five highest rates of education spending in the nation.

Anger over how the education system is managed in the staunchly conservative state has prompted the state legislature to strip the elected superintendent of schools of her main duties and cut her budget and staff while appointing an interim director of public education to serve in her stead.

The State Superintendent of Public Instruction, Cindy Hill, has countersued to block the changes, and last week Republican Governor Matt Mead announced an independent inquiry to look into employee concerns in the department.

The Wyoming debates on education mirror those nationally over standardized testing, legislative oversight, and how to best measure if progress is being made, with one key difference - the debate is raging mostly within the Republican Party.

The Republicans' conservative Tea Party faction, which normally targets excessive government spending as its signature issue, opposes transferring power from an elected official to a "government bureaucrat."

Some Wyoming lawmakers have complained that Hill has not provided necessary performance data required under federal funding requirements and has been slow to implement accountability measures they mandated.

Legislators have also complained Hill overstepped her powers when she spent $200,000 to create a new program for teacher training. Senate Education Committee Chair Hank Coe, a Republican, wants to make it tougher for teachers to gain tenure.

HIGHER SPENDING

Bubbling under the surface is the fact that per-student spending in Wyoming has increased every year over the past decade, according to the National Education Association, rising from $9,246 in 2003 to $15,997 in 2011.

A 2012 Harvard University study that tracked state trends in student performance singled out Wyoming as one of three states with large spending increases that "had only marginal test-score gains to show for all that additional expenditure."

Elected in 2010 to a four-year term, Hill was moved from a prestigious office space to more modest accommodations nearby as a result of the bill, had her budget and staff cut sharply, and was left with mostly ceremonial duties.

Hill has since filed suit to block the changes and has vowed to run for governor in 2014.

The governor has said the inquiry "allows us to shine a light on the (state education) agency, which is something that the public has asked for and is entitled to" receive. The inquiry will focus on human resources, operations and budget issues, Mead's office said.

Some legislators said during debate on the bill to strip Hill of her powers that they had heard numerous complaints from department employees about how the agency was run under Hill.

Hill said the governor's inquiry was a distraction for the department, and the result of the "political and personal agendas" of Mead and a small group of legislators.

Some Wyoming residents have expressed strong disapproval of the move to strip Hill of her duties, calling the effort an end-run around the state constitution.

"If there was a prior concern about Cindy Hill's running of the education department, why didn't they convene a panel then?" said Bob Berry, a Tea Party member who unsuccessfully challenged Coe in last year's Republican primary. "It has all been innuendo, and this doesn't wash."

(This story is corrected by deleting reference to basement office in 10th paragraph)

(Editing by Alex Dobuzinskis and Eric Walsh)

Source: http://news.yahoo.com/wyoming-bare-knuckle-fight-control-education-173705129--business.html

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A simple Facebook message from a heartbroken friend of one of the tenants who lo...

A simple Facebook... | Facebook Sign Up
  • A simple Facebook message from a heartbroken friend of one of the tenants who lost almost everything three weeks ago in a deadly fire at Huntley?s Woodcreek Apartments has snowballed into a communitywide effort. http://shawurl.com/iu2

Source: http://www.facebook.com/nwherald/posts/10151587146382573

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Saturday, February 23, 2013

First look at Apple's new iWatch (Video)


Staff Puget Sound Business Journal

Bloomberg takes a look at Apple's plans to develop an "iWatch," which would connect to a smartphone and display maps, "points of interest," even tweets.

Blogger Mikey Campbell, who writes for Appleinsider.com, describes the device based on Apple's patent filings, saying it isn't likely the full design could be made within six months or a year, but farther into the future.

Source: http://feedproxy.google.com/~r/TechFlash/~3/aCCENbjIldo/first-look-at-apples-new-iwatch.html

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Iran announces uranium finds, days before nuclear talks

DUBAI (Reuters) - Days before resuming talks over its disputed atomic program, Iran said on Saturday it had found significant new deposits of raw uranium and identified sites for 16 more nuclear power stations.

State news agency IRNA quoted a report by the Atomic Energy Organisation of Iran (AEOI) which said the reserves were discovered in northern and southern coastal areas and had trebled the amount outlined in previous estimates.

There was no independent confirmation. With few uranium mines of its own, Western experts had previously thought that Iran might be close to exhausting its supply of raw uranium.

"We have discovered new sources of uranium in the country and we will put them to use in the near future," Fereydoun Abbasi-Davani, head of the AEOI, was quoted as saying at Iran's annual nuclear industry conference.

The timing of the announcement suggested Iran, by talking up its reserves and nuclear ambitions, may hope to strengthen its negotiating hand at talks in Kazakhstan on Tuesday with the United States, Russia, China, Britain, France and Germany.

Diplomats say the six powers, known as the P5+1, are set to offer Iran some relief from international sanctions if it agrees to curb its production of higher-grade enriched uranium.

The West says Iran's enrichment of uranium to a fissile purity of 20 percent demonstrates its intent to develop a nuclear weapons capability, an allegation the Islamic republic denies.

FROM MINE TO CENTRIFUGE

The enriched uranium required for use in nuclear reactors or weapons is produced in centrifuges that spin uranium hexafluoride gas (UF6) at high speeds. The UF6 is derived from yellow cake, a concentrate from uranium ore discovered in mines.

Iran's reserves of raw uranium now stood at around 4,400 tonnes, taking into account discoveries over the past 18 months, IRNA quoted the report as saying.

In another sign that Iran is intent on pushing forward with its nuclear ambitions, the report also said 16 sites had been identified for the construction of nuclear power stations.

It did not specify the exact locations but said they included coastal areas of the Gulf, Sea of Oman, Khuzestan province and the Caspian Sea.

Iranian authorities have long announced their desire to build more nuclear power plants for electricity production. Only one currently exists, in the southern city of Bushehr, and that has suffered several shutdowns in recent months.

The announcements could further complicate the search for a breakthrough in Kazakhstan, after three unsuccessful rounds of talks between the two sides in 2012.

"We are meeting all of our obligations under the nuclear Non-Proliferation Treaty and we should be able to benefit from our rights. We don't accept more responsibilities and less rights," Saeed Jalili, Iran's chief nuclear negotiator, was quoted as telling Saturday's conference.

In what Washington has called a provocative move, Iran is also installing new-generation centrifuges, capable of producing enriched uranium much faster, at a site in Natanz in the centre of the country.

Western diplomats say the P5+1 will reiterate demands for the suspension of uranium enrichment to a purity of 20 percent, the closure of Iran's Fordow enrichment plant, increased access for International Atomic Energy Agency inspectors and agreement to address concerns on existing uranium stockpiles.

In return, the latest embargoes on gold and metals trading with Iran would be lifted. Iran has criticized the offer and says its rights need to be fully recognized.

"If the P5+1 group wants to start constructive talks with Tehran it needs to present a valid proposal," said Jalili. "It needs to put its past errors to one side ... to win the trust of the Iranian nation."

In a statement issued before the Iranian announcement, German Foreign Minister Guido Westerwelle said the six-power group wanted to enter a 'substantial negotiation process' over Tehran's nuclear program.

"The talks in Almaty are a chance which I hope Iran takes," he said.

(Additional reporting by Alexandra Hudson in Berlin; Editing by Mark Trevelyan)

Source: http://news.yahoo.com/iran-announces-uranium-discovery-days-nuclear-talks-115843696.html

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Fruit Flies Medicate Offspring With Alcohol

> The mailman himself may inhale those spores, become infected,
> become ill and, depending on the fungus, possibly die.

Fuck. Me.
I think a part of me just died,
How did we ever live?

BTW
This morning, I licked my partners cunt.
You know, the bit where she pisses from.....
I'm gonna die.

How did we ever live?
The germs...... the germs......

BTW
Are you Howard Hughes?

Source: http://rss.slashdot.org/~r/Slashdot/slashdotScience/~3/x0ZFWDEwIdI/story01.htm

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Friday, February 22, 2013

Engadget's Sony PlayStation event wrap-up broadcast: live from New York City!

The curtain has been opened, the kimono is off and everything has been revealed. Now it's time to break down all the news from Sony's PlayStation event and put it in context. Join Engadget's Tim Stevens and Joystiq's Ludwig Kietzmann in a live broadcast from New York City at the time below:

February 20, 2013 8:20 PM EST

Filed under: ,

Comments

Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/MzWtmMd1of0/

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"Vulcan" has big lead in bid to name Pluto's newly discovered moons

(Reuters) - "Star Trek" star William Shatner and tens of thousands of the show's fans are leading a charge to name one of Pluto's newly discovered moons after the character Spock's home planet.

Shatner, who played Captain James T. Kirk on the Starship Enterprise on the program launched in 1966, proposed the name earlier this month in response to an appeal from scientists for help in choosing the names of two newly discovered Pluto moons.

Vulcan is among 21 names in the running in an online poll organized by the California-based SETI Institute, whose team of astronomers discovered the moons.

As of Wednesday, Vulcan was the clear front runner, receiving more than 100,000 out of more than 330,000 votes cast.

Shatner, who starred along with Leonard Nimoy, who portrayed the Vulcan science officer Spock on the long-running TV sci-fi show, rallied support for Vulcan on Wednesday on his Twitter account, writing: "We are approaching 120K votes for Vulcan on PlutoRocks.com! Have you voted today?"

Until now, the two moons, each of which are about 15 miles to 20 miles wide, have been known as P4 and P5. The P4 moon was discovered in 2011 and P5 a year later.

Before the discoveries, astronomers had identified and named three of Pluto's moons - Charon, Nix and Hydra.

Voting for the names of the new moons ends on February 25. The selected names will be submitted to the International Astronomical Union (IAU) for consideration.

"Let's hope the IAU thinks Vulcan is a good name," Shatner said in another tweet.

(Reporting by Kevin Gray; Editing by Todd Eastham)

Source: http://news.yahoo.com/vulcan-big-lead-bid-name-plutos-newly-discovered-000422824.html

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HAPPENING NOW: Columbus Mayor Michael Coleman is giving his State of the City a...

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Source: http://www.facebook.com/WSYXABC6/posts/10151099362759364

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Tyson sues Live Nation over alleged embezzlement

In this June 18, 2012 file photo, former heavyweight boxer Mike Tyson announces "Mike Tyson: Undisputed Truth" a one man show on Broadway, in New York. Tyson and his wife sued SFX Financial Advisory Management Services, a subsidiary of Live Nation Entertainment on Wednesday Feb. 20, 2013 claiming a former employee of the financial services company embezzled more than $300,000 from them and cost them millions in lucrative contracts.(Photo by Evan Agostini/Invision/AP, File)

In this June 18, 2012 file photo, former heavyweight boxer Mike Tyson announces "Mike Tyson: Undisputed Truth" a one man show on Broadway, in New York. Tyson and his wife sued SFX Financial Advisory Management Services, a subsidiary of Live Nation Entertainment on Wednesday Feb. 20, 2013 claiming a former employee of the financial services company embezzled more than $300,000 from them and cost them millions in lucrative contracts.(Photo by Evan Agostini/Invision/AP, File)

In this June 18, 2012 file photo, former heavyweight boxer Mike Tyson announces "Mike Tyson: Undisputed Truth" a one man show on Broadway, in New York. Tyson and his wife sued SFX Financial Advisory Management Services, a subsidiary of Live Nation Entertainment on Wednesday Feb. 20, 2013 claiming a former employee of the financial services company embezzled more than $300,000 from them and cost them millions in lucrative contracts.(Photo by Evan Agostini/Invision/AP, File)

FILE - In this Saturday, Feb. 16, 2013 file photo, former heavyweight champion Mike Tyson smiles during a promotional event for former five-time champion Evander Holyfield's Real Deal barbecue sauce at a Chicago grocery store. Tyson and his wife sued SFX Financial Advisory Management Services, a subsidiary of Live Nation Entertainment on Wednesday Feb. 20, 2013, claiming a former employee of the financial services company embezzled more than $300,000 from them and cost them millions in lucrative contracts. (AP Photo/Charlie Arbogast)

(AP) ? Mike Tyson sued a financial services firm owned by Live Nation Entertainment on Wednesday, claiming one of its advisers embezzled more than $300,000 from the former heavyweight champ and cost him millions more in lost earnings.

The lawsuit claims that Live Nation and its company SFX Financial Advisory Management Enterprises haven't given the boxer and his wife, Lakiha, a full accounting of their losses. The company returned some of the embezzled money but wanted the Tysons to sign a nondisclosure agreement, which they refused, the suit states.

The lawsuit seeks more than $5 million in damages for breach of fiduciary duty, negligent hiring, unjust enrichment and other claims.

A spokeswoman for Live Nation Entertainment Inc. said the company had not been served with the lawsuit and could not comment on it.

The lawsuit claims the embezzlement prevented the Tysons from emerging from bankruptcy, and forced them to hire new advisers and turn down lucrative contracts. The couple trusted Brian Ourand, their adviser at SFX, so much that he attended their wedding, the case states.

Ourand, who could not be reached for comment, has since left SFX, according to the lawsuit. The filings claim his conduct has not been reported to regulators.

"Defendants did not secure, protect, safeguard and appropriately apply the Tysons' finances for their intended purposes," the case states, "but instead misappropriated said funds for the benefit and enrichment of SFX/Live Nation.

The former boxer has broadened his career in recent years. He appeared in "The Hangover" and is leading a one-man autobiographical show, "Undisputed Truth."

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/4e67281c3f754d0696fbfdee0f3f1469/Article_2013-02-20-People-Mike%20Tyson/id-b23713ffbedd40a3bd2589582896b503

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Bees learn the electric buzz of flowers

Floral electric fields could join color and fragrance as cues to pollinators

By Susan Milius

Web edition: February 21, 2013

Enlarge

ELECTRIC SIDE

On the right-hand halves of flowers, a dusting of electrically charged particles (color in adjacent rectangle) reveals natural patterns. Bees can sense at least simple patterns in floral electrical charges, new research says.

Credit: D. Clarke et al./Science 2013

Slight electric fields that form around flowers may lure pollinators much as floral colors and fragrances do.

In lab setups, bumblebees learned to distinguish fake flowers by their electrical fields, says sensory biologist Daniel Robert at the University of Bristol in England. Combining an electrical charge with a color helped the bees learn faster, Robert and his colleagues report online February 21 in Science.

Plants, a bit like lightning rods, tend to conduct electrical charges to the ground, Robert says. And bees pick up a positive charge from the atmosphere?s invisible rain of charged particles.

?Anything flying through the air, whether it?s a baseball, 767 jumbo jet, or a bee, acquires a strong positive electrostatic charge due to interaction with air molecules,? says Stephen Buchmann of the University of Arizona in Tucson.

Robert and his colleagues checked whether bees could choose flowers based solely on the electric fields the plants produce. Purple metal disks (encased in plastic so as not to shock bees) stood in for flowers. Half of them, wired for 30 volts, held sips of sugar water. The unwired ones offered a bitter quinine solution that bees don?t like.

Enlarge

MODEL FLOWER

A computer model predicts the electric potential of a typical flower blooming 30 centimeters above the ground (left: dark blue, 0 volts; dark red, 35 volts) and its electric field (right; dark blue, 0 volts per meter; dark red 2,000 volts per meter).

Credit: D. Clarke et al./Science 2013

Bombus terrestris bumblebees learned to chose sweet, wired disks more than 80 percent of the time. When researchers unplugged the wired disks, the bees bumbled, scoring sugar only by chance.?

?The big question is how bees do this,? says Lars Chittka of Queen Mary University of London. Bees bristle with hairs, and he speculates that a charged insect nearing an oppositely charged flower feels the hairs bend.

Electric charges of bees and flowers do interact, Robert confirmed after studying bees visiting real petunias. When a bee landed, and sometimes even before, flower stems registered an electrical surge that didn?t fade until after the bee had buzzed onward.

This surge in electric potential might tip off another passing bee that the flower had just lost nectar to a different visitor, a change that scent or color would not reveal. Roberts says, channeling a petunia: ?I?m still pretty and smell nice, but my potential tells you to come back later.?

Variations within a flower?s electric field may even hold clues to where bees should probe for nectar, Robert speculates. Researchers found striking electrical patterns when they wafted positively charged colored aerosol particles over blooms.

?I am blown away,? said Anne Leonard of the University of Nevada, Reno. ?I imagine that we?ll all be desperate to spray our flowers down with the aerosol they describe.?

Bumblebees can distinguish at least between simple electrical patterns, Robert says. They learned to fly to disks with a negatively charged bulls-eye ringed with a positive charge instead of to disks producing a uniform field.

Charge patterns can also reinforce other flower advertisements, the researchers found. Bees challenged to learn to distinguish two slightly different shades of green learned faster when researchers paired each shade with a distinctive electric charge.

In the real world, bees face a marketing barrage of combined scents, colors and other cues from flowers. ?One open question in behavior is when are such cues used, and when are they ignored,? says Robert Raguso of Cornell University. Pollinators need to find their next meal before they run out of fuel, and if a cue such as humidity or electrical charge can let them make snap judgments to save resources, he predicts bees would pay attention.


A.S. Leonard and D.R. Papaj. ?X? marks the spot: The possible benefits of nectar guides to bees and plants. Functional Ecology. Vol. 25, 2011, p. 1293. doi: 10.1242/jeb.047407.

M. von Arx et al. Floral humidity as a reliable sensory cue for profitability assessment by nectar-foraging hawkmoths. Proceedings of the National Academy of Sciences. Vol. 109, June 12, 2012, p. 9471. doi: 10.1073/pnas.1121624109 [Go to]

R. Ehrenberg. Jiminy Cricket! Pollinator caught in the act. Science News Online. Posted Jan.18, 2010. [Go to]

S. Milius. Big study?Selective pollinators are declining. Science News. Vol. 170, July 22, 2006, p. 51. [Go to]

Source: http://www.sciencenews.org/view/generic/id/348490/title/Bees_learn_the_electric_buzz_of_flowers

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Nko est demande sur Windows phone [updated]

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Source: http://windowsphone.uservoice.com/forums/101801-feature-suggestions/suggestions/3676835-nko-est-demande-sur-windows-phone

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Thursday, February 21, 2013

Trans Mountain oil pipeline apportioned for March

CALGARY, Alberta, Feb 21 (Reuters) - Kinder Morgan Energy Partners LP said on Thursday that shippers on its routinely overbooked Trans Mountain oil pipeline system between Alberta and the Pacific Coast will be limited to only 33 percent of their hoped-for volumes in March.

Kinder Morgan said capacity on the system, which carries Canadian crude to the Vancouver-area and Washington state refineries, was over-nominated by 67 percent.

Nominations have exceeded capacity since late 2010.

For next month, Kinder Morgan said total accepted nominations for the system are 290,663 barrels per day for the Trans Mountain pipeline, 134,662 bpd for the Puget Sound line and 78,207 bpd for the Westridge Dock.

(Reporting by Scott Haggett) Keywords: KINDERMO0RGAN TRANSMOUNTAIN/

(scott.haggett@thomsonreuters.com)(Twitter @scotthaggett)(+1 403 531-1622)(Reuters Messaging: scott.haggett.thomsonreuters.com@reuters.net)

COPYRIGHT

Copyright Thomson Reuters 2013. All rights reserved.

The copying, republication or redistribution of Reuters News Content, including by framing or similar means, is expressly prohibited without the prior written consent of Thomson Reuters.

Source: http://www.xe.com/news/2013/02/21/3217577.htm?utm_source=RSS&utm_medium=TL&utm_content=NOGEO&utm_campaign=News_RSS_Art1

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Tuesday, February 19, 2013

Mainers take part in climate rally in Washington

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Vt. hopes syrup grade changes will sweeten sales

In this Friday, Feb. 15, 2013 photo, four grades of maple syrup are displayed in a gift box in East Montpelier, Vt. Vermont lawmakers are considering whether to drop the state's traditional maple labeling system in favor of an international one. (AP Photo/Toby Talbot)

In this Friday, Feb. 15, 2013 photo, four grades of maple syrup are displayed in a gift box in East Montpelier, Vt. Vermont lawmakers are considering whether to drop the state's traditional maple labeling system in favor of an international one. (AP Photo/Toby Talbot)

In this Friday, Feb. 15, 2013 photo, four grades of maple syrup are displayed in a gift box in East Montpelier, Vt. Vermont lawmakers are considering whether to drop the state's traditional maple labeling system in favor of an international one. (AP Photo/Toby Talbot)

In this Friday, Feb. 15, 2013 photo, 18 different grades of maple syrup are displayed in East Montpelier, Vt. Vermont lawmakers are considering whether to drop the state's traditional maple labeling system in favor of an international one. (AP Photo/Toby Talbot)

(AP) ? Would fancy grade maple syrup by any other name taste as sweet?

Vermont lawmakers are pondering that question as they consider whether to drop the state's traditional maple labeling system in favor of an international one.

The change pits tradition versus a desire to be a bigger player in world markets. Vermont is the No. 1 maple syrup producer in the United States, but its unique labeling standards put it at odds with the other big producers, including Canada.

The state Senate last week passed and sent to the House a measure to drop fancy, grade A medium amber, dark amber and grade B. (Fancy is the lightest and mildest, while grade B is the darkest and has the strongest maple flavor.) In their place would be several types sharing a grade A label, with descriptive phrases following: golden color and delicate taste; amber color and rich taste; dark color and robust taste; very dark color and strong taste.

Sen. Kevin Mullin, R-Rutland, initially argued against the measure before reluctantly going along.

"We should not be following everyone else in lockstep and ... giving them the ability to try to pretend that syrup made in another state is anywhere near as good as the syrup made in Vermont," he said.

Mullin later said he was mollified by assurances that the changes would be phased in over three years and that producers wouldn't have to throw out containers already printed with the existing labels.

State Agriculture Secretary Chuck Ross said the changes have largely been pushed by the industry, though the agency has conducted a series of public hearings to address the concerns of the more reluctant producers.

Thanks to improvements in technology and growing interest by landowners, Vermont's syrup production has roughly doubled in the past decade, to the extent that supply vastly exceeds any demand that would come from a state of about 626,000, Ross said.

"What's become clear is that the majority of syrup produced in the state of Vermont is sold in national and international markets," Ross said.

Vermont will maintain its distinct branding by labeling its syrup as coming from the state. Connoisseurs will continue to appreciate that Vermont regulations will continue to require boiling sap for longer than is the case elsewhere, producing a slightly denser product, Ross said. But to continue using a separate grading system would lead to consumer confusion, the secretary added.

Doug Bragg, an eighth-generation syrup producer from East Montpelier, said he was taking the changes in stride.

"Most of our customers are asking, why do we have to do this? There's a logic to it, no question about it," Bragg said. "It's still annoying though."

Back at the Senate office, where Lt. Gov. Phil Scott was chatting Friday afternoon with the five-member staff, there was broad agreement that people would get used to the changes. The only real debate was over the best grade.

Office assistant Roxy Quero said her preference was for fancy grade, but Scott said he preferred medium amber. Deputy Senate Secretary Steve Marshall said the darker the better for him.

"I usually go with grade B, grade C if I can get it, but you have to know somebody," Marshall said. "Grade C isn't sold as syrup at retail; it's usually use in baked goods or maple candy.

"I'd take double D if you gave me some," Marshall said.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2013-02-18-Food%20and%20Farm-Maple%20Grading/id-3916402d7bc3455d8c8ef7e01a40a216

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Monday, February 18, 2013

Obama to Intensify China Containment, Version 2.0

Huanqiu,?China

Obama to Intensify China Containment,
Version 2.0


By Fu Meng Zi

The politicians of both countries must face facts; the profit-making mechanisms of both countries are predicated on the condition of ample collaboration.

Translated By Chase Coulson

29 January 2013

Edited by Heather Martin


China - Huanqiu - Original Article (Chinese)
The New US Agenda, a Response to China?s Explosive Rise

Obama recently began his second term in office. Relatively speaking, between the two terms there should be continuity of diplomatic policy, yet there will still likely be some adjustments included in new policy regarding China. The U.S. has always pursued the position of ?world leader,? and that's a goal that won't change anytime soon. Due to the continual expansion of China?s influence, it has been moved to a prominent position of consideration within the U.S. global strategy. How China?s rise should be dealt with, if it?s not to be not included among the U.S.? most pressing diplomatic policies, is certain to be one of the main policies on the agenda.

Regardless of whether it is on the international, multilateral or regional level, or even the country level, the China factor will occupy much more space on the U.S. foreign policy agenda this term. In Obama?s ?return to Asia? strategy, there has been a constant push to balance or negate China?s influence, which is clearly and unmistakably at the heart of its strategic concerns. The U.S.? entry into the South China Sea islands dispute and other such affairs has intensified suspicions in Sino-American strategic interaction. The U.S. is fully aware of the possibility of creating tension and danger as a result of its global strategy. The ?return to Asia? strategy will not change. There is, however, a crucial problem with regard to the ?Asia re-balancing,? which is that military tactics will no longer be given sole prominence; economic, political and diplomatic tactics will also be brought into play to add additional impetus to the re-balance.

In Obama?s second term, there will be a major reshuffling of cabinet members, which includes the secretary of state, director of commerce and the CIA director, among others. As president, Obama always holds the reins in U.S. diplomatic policy decisions. With only personnel changes, there will be no substantial revisions made to the U.S.? China policies, but the U.S. is facing a problem with its China ?re-balancing? policies, specifically avoiding any excessive turbulence or retrogression in Sino-U.S. relations. To that end, at least it should play down the fact that it?s surrounding China on all sides throughout Southeast Asia. Due to the fact that the two countries have such a high degree of interdependence, bilateral relations should be handled with the utmost care. After beginning his visit and a series of interviews in China, Assistant Secretary for East Asian and Pacific Affairs Kurt M. Campbell expressed that China and the U.S. have established a positive and comprehensive collaborative relationship and so great pains should be taken to avoid creating conflict between the existing superpower and the emerging one.

Sino-American Relations Enter Uncharted Waters

The current differences between the U.S. and China have always been there, but because both sides have laid the foundation for cooperative strategy during different periods, these differences have not affected positive collaboration between our two nations. Some analysts believe both the U.S. and China are currently entering ?uncharted waters.? There have been almost five decades of Sino-American relations thus far; for the first time our two nations lack a ?great common goal? ? i.e. resisting the threat of the Soviet hegemony and crackdowns on terrorism, etc. ?that we once had. In other words, we now lack a common platform for cooperation. During the televised presidential debates, Obama's description of China as an ?opponent and potential partner? fell short of accurately describing the current conditions of the complex and multifaceted development of Sino-U.S. relations. But it is not possible for the background of this ?opponent and potential partner? theory to be taken strictly on the basis of one issue alone, moreover the theory conceals Obama's actual stance on China?s strategy. If, on account of these decisions, the U.S. develops an attitude of uncertainty toward Sino-U.S. constructive collaboration ? despite the fact that the association between our two countries will deepen ? at the same time the U.S.' ability to inhibit and hedge China will increase during this second term.

Of course it doesn?t mean that our two countries are on the verge of a head-on collision, for the two nations to enter into a state of war is absolutely not a possible, feasible or even imaginable prospect. The U.S. containment of China will most likely unfold in an indirect and roundabout manner, for instance, intervening in island disputes between China and neighboring states.

Due to the strategic demands involved in restricting China, it is difficult for the U.S. to stay neutral on the Diaoyu Islands issue. During the 2013 fiscal year, the U.S. Senate ratified the National Defense Act, which amended the stipulations applicable to the Diaoyu Islands in the fifth paragraph of the U.S.-Japan National Security Alliance Treaty amendment. On January 18 Secretary of State Hilary Clinton recognized the islands as being under Japan's jurisdiction. This and many other cases make it plainly evident that the U.S.? restrictions of China will tighten up in the future. Of course in this issue ?cautious intervention + re-balance containment + prevention of loss of control? will be the U.S. government's all-important strategic formula. Furthermore, the island dispute issue will be the fulcrum in bringing certain Asian countries into the fold. It goes without saying that keeping China in check is a major strategic goal.

Moreover, some new developments in the U.S.? strategies with respect to China have presented themselves. Over the long term, U.S. policy goals will be to meld China into its international economic order; whether or not the current order continues remains to be seen. Recently, large Chinese companies like Huawei have been shut out of the U.S. market on account of safety concerns, which indicates that the U.S. has developed a counter-globalization attitude. U.S. consumer products are still the world's most influential, but the U.S. desire to develop into the ?benign hegemon? is waning. At the outset of the U.S.? Trans-Pacific Partnership, China will be excluded ? this implies something other than business as usual. And although recently the U.S. has exhibited openness toward China joining, a very high hurdle has been set for Chinese state-owned enterprises, government procurements, labor standards, etc., and of course this means [the policies] are aimed directly at causing China to shrink back.

Sino-US Relations: Not a Matter of Who's Chasing Whom

In a globalized world it is normal for every country to rely on heightened friction and competition between one another, and our two countries are no exception. What we should be on guard against, however, is the politicization of trade. Pointlessly passing the buck makes it all the easier for bilateral issues to become part of a domestic political agenda, which may lead the decisions of the average citizen astray.

The politicians of both countries must face facts; the profit-making mechanisms of both countries are predicated on the condition of ample collaboration. There is a strong possibility of long-term friction, and at times this reality might intensify. We should adopt a straightforward attitude, keep our eyes fixed upon the long-term gains of both countries and, for the sake of cooperation and development, work out the differences in our bilateral relations. Version 2.0 of Obama's diplomatic strategy as it relates to China will be subordinated to the demands of realism and may at times stress the demand for ?controllability.?

What's worth mentioning at this point is that today's Sino-U.S., or U.S.-Sino relations if you will, are not biased; it's not a matter of who's chasing whom. The problems on both sides are unbiased. In response to the great challenge of situations like global warming and in response to traditional safety challenges, it's even less so. China's ability to create a U.S. policy model is a far cry from that of yesteryear. Even Obama's own high-level Chinese affairs consultant Jeff Bader believes that the ?variable? in the development of U.S.-Sino relations is skewed toward the China side. Obviously the adjustment in U.S. policy with respect to China is also related to China's policy toward the U.S. Moreover, Chinese policy toward the U.S. shows stronger ?inheritability.? Sino-U.S. relations are actually still looking toward favorable developmental opportunities.

The author is vice president and researcher at the China Institute of Contemporary International Relations.

CLICK HERE FOR ORIGINAL VERSION

Source: http://watchingamerica.com/News/195610/obama-to-intensify-china-containment-version-2-0/

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Sunday, February 17, 2013

Researchers create new air sacs in mouse model of emphysema using novel growth factor

Researchers create new air sacs in mouse model of emphysema using novel growth factor

Friday, February 15, 2013

In a study of mice, researchers at Johns Hopkins have identified a new molecular pathway involved in the growth of tiny air sacs called alveoli that are crucial for breathing. The scientists say their experiments may lead to the first successful treatments to regrow the air sacs in people who suffer from diseases such as emphysema in which the air sacs have been destroyed by years of smoking. The work may also suggest new therapy for premature infants born before their lungs are fully developed.

"One of the most daunting challenges we face as physicians is helping patients with chronic obstructive pulmonary disease, such as emphysema, who have lost alveoli that are so crucial for lung function," says Enid Neptune, M.D., associate professor of pulmonary and critical care medicine at the Johns Hopkins University School of Medicine. "Once those tiny air sacs are destroyed, there are no effective treatments to bring them back."

Neptune is the senior author of a study described in an article in the Feb. 14, 2014 issue of PLOS Genetics in which the researchers used hepatocyte growth factor (HGF) to regrow alveoli and restore lung structure in mice genetically engineered to develop a human-like form of emphysema. Theirs is believed to be the first study using HGF in mice with established emphysema.

Growth factors, such as HGF, have been used to promote wound healing. Neptune says previous studies had shown that HGF had a role in the functioning of alveoli, which enable lungs to exchange oxygen and carbon dioxide and send oxygen into the bloodstream to nourish organs throughout the body. Reduction in the number or quality of the sacs seriously compromises breathing.

Even though they cannot be seen by the naked eye, tiny, spherical alveoli are covered with thin walls and have a blood supply. The researchers conducted experiments in mice with a genetically induced form of emphysema to see if HGF could stimulate the formation of alveoli.

One experiment involved adult mice with genetically induced emphysema. Half of the mice received HGF, delivered under the skin using a special pump for two weeks. The other half of the group received a placebo ? not the HGF. Another group of mice with healthy lungs, the "control" group, was divided in half to receive either HGF or a placebo.

"We found that the mice with emphysema, when given the HGF, developed a 17 percent improvement in the size of their air sacs compared to placebo-treated mice, consistent with improved lung structure and function. The HGF also was protective, preventing destruction of the alveoli by reducing the oxidative stress that contributes to lung injury," says Neptune. "In essence, the HGF was able to block a major enemy of the functioning alveoli."

In addition, the healthy mice that received HGF showed no difference in alveolar size. The mice with emphysema that were treated with a placebo did not show any improvement.

The researchers then wanted to see the effect of impaired HGF activity in young mice whose lungs were still forming. They created a mouse in which the HGF receptor, known as MET, was removed from the cells lining the alveoli. "Our idea was if HGF was performing this important role in alveoli formation, if we knocked out its receptor, known as MET, we should see damage to the alveoli," says Neptune.

As predicted, the air sacs in the developing mice without the HGF receptor did not form correctly. Also, the blood vessels serving the alveoli were reduced and there was an increase in both oxidative stress and inflammation. The researchers concluded that developing alveoli require both HGF and MET signaling in order to form normally.

"Our research is an important demonstration that a growth factor can be used as a drug for emphysema," Neptune says. "However, since HGF reduces cell death and promotes cell proliferation, we would have to be cautious about translating it to the smoking population where there's a higher risk of lung cancer." she adds. Neptune and others are pursuing research to be able to selectively activate the therapeutic and not the malignancy-inducing components of HGF signaling.

Emphysema is a form of chronic obstructive pulmonary disease (COPD), which is the third-leading cause of death in the United States. An estimated 30 million Americans have COPD and about 60,000 people die from it each year. In addition to smoking, occupational exposure to harmful dust, fumes and smoke can also cause COPD.

###

Johns Hopkins Medicine: http://www.hopkinsmedicine.org

Thanks to Johns Hopkins Medicine for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

This press release has been viewed 45 time(s).

Source: http://www.labspaces.net/126848/Researchers_create_new_air_sacs_in_mouse_model_of_emphysema_using_novel_growth_factor

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Friday, February 15, 2013

Scientists create method to personalize chemotherapy drug selection

Friday, February 15, 2013

In laboratory studies, scientists at the Johns Hopkins Kimmel Cancer Center have developed a way to personalize chemotherapy drug selection for cancer patients by using cell lines created from their own tumors.

If the technique is successful in further studies, it could replace current laboratory tests to optimize drug selection that have proven technically challenging, of limited use, and slow, the researchers say.

Oncologists typically choose anticancer drugs based on the affected organs' location and/or the appearance and activity of cancer cells when viewed under a microscope. Some companies offer commercial tests on surgically removed tumors using a small number of anticancer drugs. But Anirban Maitra, MBBS, professor of pathology and oncology at the Johns Hopkins University School of Medicine, says the tissue samples used in such tests may have been injured by anesthetic drugs or shipping to a lab, compromising test results.

By contrast, he says "our cell lines better and more accurately represent the tumors, and can be tested against any drug library in the world to see if the cancer is responsive."

The Johns Hopkins scientists developed their test-worthy cell lines by injecting human pancreatic and ovarian tumor cells into mice genetically engineered to favor tumor growth. Once tumors grew to one centimeter in diameter in the mice, the scientists transferred the tumors to culture flasks for additional studies and tests with anticancer drugs.

In one experiment, they successfully pinpointed the two anticancer drugs from among more than 3,000 that were the most effective in killing cells in one of the pancreatic cancer cell lines. A report on the success was published online Jan. 22 in the journal Clinical Cancer Research.

The new method was designed to overcome one of the central problems of growing human tumor cell lines in a laboratory dish -- namely the tendency of noncancerous cells in a tumor to overgrow cancerous ones, says James Eshleman, M.D., Ph.D., professor of pathology and oncology and associate director of the Molecular Diagnostics Laboratory at Johns Hopkins. As a consequence, it has not been possible to conventionally grow cell lines for some cancers. Still other cell lines, Eshleman says, don't reflect the full spectrum of disease.

To solve the problem of overcrowding by noncancerous cells, Maitra and Eshleman bred genetically engineered mice that replace the noncancerous cells with mouse cells that can be destroyed by chemicals, leaving pure human tumor cells for study.

"Our technique allows us to produce cell lines where they don't now exist, where more lines are needed, or where there is a particularly rare or biologically distinctive patient we want to study," says Eshleman.

In its proof of concept research, the Johns Hopkins team created three pancreatic ductal adenocarcinoma cell lines and one ovarian cancer cell line. They then tested one of the pancreatic cancer cell lines (called Panc502) against the Johns Hopkins Drug Library of 3,131 drugs, identifying tumor cells most responsive to the anticancer drugs digitoxin and nogalamycin.

For 30 days, they watched the effects in living mice of the two drugs and a control medicine on tumors grown from implanted cells derived from Panc502 and an additional pancreatic cell line, Panc410. They measured the size of tumors twice a week. Both drugs demonstrated more activity in reducing the tumor appearance and size in Panc502 than in Panc410, supporting the notion that the cell line technology may better predict sensitivity to the two drugs.

The investigators have given one type of their genetically engineered mice to The Jackson Laboratory in Bar Harbor, ME, a mouse genetics research facility, for breeding and distribution to other laboratories and are looking to partner with a company to distribute two other types.

###

Johns Hopkins Medicine: http://www.hopkinsmedicine.org

Thanks to Johns Hopkins Medicine for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

This press release has been viewed 13 time(s).

Source: http://www.labspaces.net/126826/Scientists_create_method_to_personalize_chemotherapy_drug_selection

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Happy Valentine's Day! Today's Facebook Friend of the Day is Nicole Marshall!...


Happy Valentine's Day! Today's Facebook Friend of the Day is Nicole Marshall!

"I follow your stories on Facebook and I enjoy reading your news feed, and It would be fun to have my profile on the news feed and have that recognition for one day."

Thanks for following 11Alive on Facebook Nicole!

? with Nicole Marshall.

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Thursday, February 14, 2013

healthfinder.gov - Cancer Chemotherapy Tied to Slight Rise in Risk ...

THURSDAY, Feb. 14 (HealthDay News) -- Chemotherapy can be a lifesaver for thousands of cancer patients, but a new study suggests that it might slightly raise the odds for a type of leukemia later in life.

Over the past 30 years, the risk for acute myeloid leukemia (AML) has increased for patients who underwent chemotherapy for certain forms of cancer, particularly non-Hodgkin lymphoma, the new study found.

On the other hand, the researchers from the U.S. National Cancer Institute said other cancer survivors may have a reduced risk for AML due to a change in chemotherapy agents that occurred decades ago.

One expert not connected to the study stressed that cancer patients need to put the findings into perspective.

"It's important to realize that the risk of developing acute myeloid leukemia related to prior chemotherapy is small and increases with the number of chemotherapy treatments given over time," said Dr. Jonathan Kolitz, chief of hematologic oncology at the North Shore-LIJ Cancer Institute in Lake Success, N.Y.

The study was published online Feb. 14 in the journal Blood.

The findings aren't a big surprise to oncologists.

"It has long been known that some types of chemotherapy are associated with a high risk of developing subsequent leukemia," explained study lead author Lindsay Morton, in NCI's Radiation Epidemiology Branch in the Division of Cancer Epidemiology and Genetics, in an NCI news release. "The goal of this study was to better understand how cancer patients' risk of developing leukemia has changed over time."

In conducting the study, the researchers assessed the risk for leukemia of more than 426,000 adults who received chemotherapy for cancer diagnosed between 1975 and 2008. Of these patients, 801 went on to develop AML.

Patients who survived non-Hodgkin lymphoma were at greater risk for AML, the team found. According to the researchers, that may be due to prolonged survival for forms of the disease that require multiple courses of chemotherapy.

Since 2000, patients treated for esophageal, prostate and cervical cancer were also found to be at greater risk for AML, the researchers say. The study also showed that those treated for cancer since the 1990s for cancers of the bones and joints, as well as the endometrium (uterine lining), are also at increased risk for AML.

Meanwhile, patients treated for ovarian cancer, myeloma, and possibly lung cancer may be at reduced risk for AML. The researchers suggested the lower risk among patients with these forms of cancer may be linked to a treatment switch that occurred in the early 1980s from an agent called melphalan to newer, platinum-based chemotherapy.

More research is needed to determine the risks associated with various chemotherapy agents, the researchers said.

For his part, Kolitz said that it is "gratifying to see that the likelihood of developing leukemia from the treatment of several of the studied cancers actually fell over the last decade, very likely because of decreased use of drugs that are most potently [linked to leukemia risk]."

Another expert agreed that the overall risk to any one cancer patient is small.

"This study confirms that a very small number of patients may be at risk for the development of a second cancer due to the effects of chemotherapy," said Dr. William Carroll, a pediatric oncologist at NYU Langone Medical Center, in New York City.

"Patients should always ask their doctor about the risk of serious side effects associated with particular parts of therapy, and whether agents with fewer side effects can be substituted without compromising the best chance for cure," said Carroll, who is also director of the NYU Cancer Institute and a professor at the NYU School of Medicine.

"Finally," he added, "it is increasingly clear that certain patients may be more likely to experience certain side effects based on their own genetic makeup. The ability to determine who is at greatest risk [via genetic testing], thereby allowing therapy to be tapered is one of the fundamental goals of personalized medicine."

More information

The U.S. National Cancer Institute provides more information on leukemia.

SOURCE: Jonathan Kolitz, M.D., associate chief, hematologic oncology, North Shore-LIJ Cancer Institute, Lake Success, N.Y.; William L. Carroll, M.D., pediatric oncologist, NYU Langone Medical Center, and director, NYU Cancer Institute, and professor, NYU School of Medicine, New York City; U.S. National Institutes of Health, news release, Feb. 14, 2013

Copyright ? 2013 HealthDay. ?All rights reserved.

HealthDayNews articles are derived from various sources and do not reflect federal policy. healthfinder.gov does not endorse opinions, products, or services that may appear in news stories. For more information on health topics in the news, visit Health News on healthfinder.gov.

Source: http://healthfinder.gov/News/Article.aspx?id=673437

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Asher Levine's fall 2013 fashion line goes future forward

Asher Levine

Children of the '80s, you'll want to remember this name: Asher Levine. He's the young designer behind an also young label poised to make Marty McFly's vacuum-powered jacket from Back to the Future Part II a real-life retail item. But more on that in a bit. As you might've already guessed, Levine's brand is atypical of the industry, one based upon the incorporation of technology and innovation with style. It sounds strange when you consider this is fashion we're talking about -- a notoriously stodgy industry predicated upon its historical archives -- but then again, this is the very same designer that teamed up with MakerBot for his fall 2012 collection. Oh, and did we mention he dresses the likes of Lady Gaga and will.i.am? There's that, too.

While that last crossover collaboration employed MakerBot's Replicator for 3D-printed eyewear, Levine's current fall / winter 2013 line is taking things into a less cumbersome, more practical realm. Through a partnership with Phone Halo, a company focused on mobile Bluetooth solutions, apparel in this new collection will feature integrated tracking chips to help high-end clientele locate lost or misplaced luxury items via a customized TrackR app. So forget about last season's trends, Levine is committed to pushing things forward, while also daring to dream a little sci-fi dream.

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Source: http://www.engadget.com/2013/02/13/asher-levine-fall-2013-fashion-line-goes-future-forward/

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Tied-up couple key to ending manhunt

NBC News

Karen and Jim and Reynolds.

By Tracy Connor and Matthew DeLuca, NBC News

The chase, shootout, standoff and inferno that ended the search for ex-LAPD officer Christopher Dorner began when a married couple startled the suspect in his mountainside hideout.

When Karen and Jim Reynolds arrived to tidy their rental cabin not far from a police command post, they found the alleged cop killer holed up inside.


?He said four or five times that he didn't have a problem with us, he just wanted to clear his name,? said Jim Reynolds at a press conference late Wednesday. ?He said I don't have a problem with you so I?m not going to hurt you.?

?I didn't believe him, I thought he was going to kill us,? he added.

?

Karen and Jim Reynolds, the couple who accidentally stumbled upon fugitive Christopher Dorner, describe finding him, being tied-up, what he said to them, and their eventual escape.

Dorner, the target of the biggest manhunt in LAPD history, then tied them up, swiped their purple Nissan Rogue SUV and left.

"We haven't really been told what's happened to it," said Karen Reynolds.

Dorner might have had a chance to flee the Big Bear ski resort area where scores of police had conducted a door-to-door search for him ? except Karen Reynolds got free, called 911 and alerted cops that a man who looked like Dorner was on the run, the officials said.

After a long manhunt culminating in gunfire and a cabin set ablaze, the search for accused murderer and ex-cop Christopher Dorner seems to have ended. Police say the charred body found inside the cabin was unrecognizable, but they claim there is no doubt their suspect is dead. NBC's Miguel Almaguer reports.

"What we did was kind of scoot our way ? I went up and she went down," said Jim Reynolds. "then she got her gag off and then we both worked on trying to stand up."

Earlier reports, based on statements from law enforcement officials, indicated that it was a pair of housekeepers who had been tied up by the suspect.

"We really very much wanted to clarify things," said Karen Reynolds, "but, it was taking us a whole lot of time to get over the trauma too and, like even by the time all the police were gone last night you guys [reporters] arrived immediately and, wasn't, we never slept for one second, since this happened."

The 911 call set in motion a dramatic and tragic chain of events in which one sheriff?s deputy was killed in a gun battle outside a second cabin where the suspect?s charred body would be found before the day?s end.

?It was like a war zone and our deputies continued to go in to that area,? San Bernardino County Sheriff John McMahon said at a press conference Wednesday afternoon. ?The rounds kept coming, but our deputies didn?t give up.?

Police have not officially determined that the corpse found in the burned-out county was Dorner, who kept southern California in fear for a week as, authorities say, he carried out a murderous campaign of revenge against the LAPD. They are waiting for forensics.

The San Bernardino Sheriff?s office has said they don?t believe the gunman who barricaded himself inside the cabin escaped before it erupted in flames.

?We believe that this investigation is over at this point and we?ll need to move on from here,? said McMahon.

McMahon said police did not intentionally set the cabin ablaze, but the pyrotechnic tear gas canisters ? commonly referred to as ?burners,? he said ? generate a high level of heat.

?It was when police began using the pyrotechnic canisters to flush out the suspect that the fire began.

The charred remains of the cabin where ex-cop Christopher Dorner was believed to have been holed up.

The LAPD, which had been under a series of tactical alerts while Dorner was on the lam has returned to normal operations on Wednesday, although a dozen people on hit list remained under guard, said Lt. Andy Neiman.

"Thanks to the brave men and women of the San Bernardino Sheriff's Department, it looks like we have our man," Los Angeles Mayor Antonio Villaraigosa said on MSNBC's "Morning Joe" early Wednesday.

Investigators had been combing the ski resort area since Thursday, when Dorner?s burned out Nissan truck was found there hours after he allegedly ambushed cops in two cities, killing Officer Michael Crain.

Days earlier, police believe, Dorner executed the daughter of a retired police captain and her fianc? in Irvine to kick off a killing spree that sowed fear across the region and in the ranks of law-enforcement.

After the man believed to be Dorner fled the cabin where he had encountered the couple, wardens from the California Department of Fish and Wildlife spotted the purple Nissan and gave chase.

The suspect lost them and, it appears, ditched the Nissan and carjacked a white pickup.

Rick Heltebrake, 61, told TODAY on Wednesday that he was driving near the Boy Scout camp he operates when a heavily armed man he recognized as Dorner, 33, crawled out of the woods, pointing a rifle at him.

He said the hulking former Navy reservist was wearing camouflage and a ballistics vest and told Heltebrake, ?I don?t want to hurt you.?

?He was dressed for action,? Heltebrake said.

Dorner commandeered the pickup, but let the man and his dog go. Shortly after Dorner sped off, Heltebrake heard gunshots.

That may have been the brief exchange of fire between Dorner and another game warden who spotted the pickup and pursued it. The warden?s truck was riddled with bullets, but he was not hurt, officials said.

Dorner then ?fled into the forest and barricaded himself inside a cabin,? the San Bernardino Sheriff?s office said. ?A short time later there was an exchange of gunfire between law enforcement and the suspect.?

KNBC-TV

Det. Jeremiah MacKay, 35, was killed on Feb. 12, 2013, after exchanging gunfire with a man believed to be a fugitive ex-police officer accused of a revenge-motivated shooting spree.

Two deputies were shot and taken to Loma Linda University Hospital, where officials later confirmed sheriff?s deputy Jeremiah MacKay had died and another had surgery but was expected to survive.

MacKay, 35, joined the department in 1998 and was father to a 7-year-old daughter and 4-year-old son.

?Our department is grieving from this event,? said McMahon.

No further shots were fired from the Angelus Oaks cabin before police began to storm the building, according to a sheriff?s spokesman.

Deputies smashed the cabin?s windows, fired in tear gas, and tore through the structure?s walls using an armored personnel carrier, a source close to the probe told?NBCLosAngeles.com. A single gunshot then rang out, according to the source, and flames and smoke began to emerge from the remains of the building.

It was hours before police were able to enter the cabin and find the body. Investigators continued to scour the crime scene Wednesday as other police gathered in Riverside for the funeral of Officer Crain.

San Bernardino, Calif., County Sheriff John McMahon says that the sheriff's department did not intentionally burn down a California mountain cabin where Christopher Dorner is believed to have died. Watch the entire news conference.

Neiman said it was difficult to celebrate the apparent end to the rampage given the loss of four lives, two of them lawmen.

?This has been a very trying time,? he said. ?To hear those words ?officer down? is the most gut-wrenching experience you can have as a police officer,? Neiman said.

Additional reporting by Andrew Rafferty

This story was originally published on

Source: http://usnews.nbcnews.com/_news/2013/02/13/16953061-tied-up-couple-key-to-ending-manhunt?lite

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